Have any large Mobile Game Developers tested Mobile Web Native, and if yes how did it go?

Sure, I've worked with gaming companies that have run ads on Taboola and Outbrain, but I've never seen either of those channels represent a meaningful amount of spend for a gaming company. It takes a lot of work to iterate into performant a. creatives and b. targeting on those channels and the funnel tends to be very inefficient. When I have seen this be profitable (at low-ish scale), the games were core with very deep monetization.